Email sign-offs — 80+ ways to close an email, ranked by when to use them.
The sign-off is a two-word decision that quietly frames everything above it. "Best regards" is a completely different message than "cheers", and both are different from no sign-off at all. This is the honest guide — six categories, when each works, when each backfires, and how the sign-off relates to the signature block underneath.
Formal & safe
First contact with someone senior, external clients, legal or finance context. Boring is the point — you're being read for competence, not personality.
Warm professional
Internal team, ongoing client relationships, colleagues you've met. Adds a touch of humanity without crossing into casual.
Casual & friendly
Colleagues you know, informal team chats, follow-ups on already-warm threads. Skip these on cold outreach.
Context-specific
The sign-off that names the reason for writing. Often more effective than a generic one.
Gen Z / very online
Internal team where humour lands, community DMs, Discord-adjacent professional contexts. Wrong to strangers and wrong to leadership.
Sign-offs to avoid
These make you look sloppy, passive-aggressive, or oblivious. Don't.
Frequently asked
›Is 'Best regards' still the best default sign-off?
For any first contact, external message, or context you're unsure about — yes. It's the closest thing to a universally-safe choice in professional English. Nobody has ever been fired for using 'Best regards'. That's not a bug, it's the whole point.
›What's a good alternative to 'Best regards' that isn't stuffy?
'Thanks,' for anything with a request in it; 'All the best,' for warm-but-professional; 'Regards,' if you want to shorten without switching tone. All three are safe in almost any US or UK business context.
›Should I always sign off, or can I skip it in casual replies?
On any thread that's already been going, a one-line reply without a sign-off is fine — you already established the relationship. On any first message, a sign-off is expected. Skipping it in a first email reads as either curt or careless.
›Do email sign-offs even matter anymore?
They matter more than the copy of them suggests. A study by Boomerang (analysing 350K email threads) found emails ending in 'thanks in advance' got a 65.7% response rate vs 51% for 'best'. The sign-off frames the ask. Choose intentionally.
›What's the difference between 'Best' and 'Best regards'?
'Best' is the abbreviated Silicon Valley variant — faster, less formal, common in tech. 'Best regards' is the fuller, more traditional form. Same intent, different register. Match your team's convention.
›How does the sign-off relate to my email signature?
They're separate. The sign-off is the closing phrase you type ('Best regards,'); the signature is the block below it (name, title, contact, banner). A good signature makes the sign-off feel finished — no signature and 'Best regards,' looks abrupt on longer messages.